What concept did Emil du Bois-Reymond theorize to explain neuron signaling?

Emil du Bois-Reymond is primarily known for his foundational work in electrophysiology, particularly in his investigations into how electrical signals are generated and conducted in the nervous system. The correct answer, synapse, relates closely to his contributions because while he didn't specifically discover synapses as understood today, he laid important groundwork for understanding how neurons communicate.

Du Bois-Reymond's experiments demonstrated that neurons can generate electrical impulses, which are crucial for signaling. He studied the properties of nerve impulses, and while he described electrical conduction along neurons, his work ultimately contributed to later developments around the concept of synapses — the junctions where neurons communicate with each other.

This reflects his influence on the field as he sought to understand how nerve cells work together rather than just focusing on individual neuron function or structure. His research helped set the stage for further investigation into neurotransmitters and the specifics of neuronal communication that would follow in later scientific advancements.